gb88

gb88B ) PAR2 antagonist GB88 (1.6 Ϯ 0.5 ␮ M) was 1000-fold more potent than ENMD-1068 (1.2 Ϯ 0.4 mM) in preventing trypsin-induced intracellular calcium release ([Ca 2 ϩ ] i ) in HMDMs ( n ϭGB88 snificantly reduced osteoclastic alveolar bone loss in mice infected with P. gingivalis, seemingly by preventing the upregulation of several